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February 2008 Comment: Microarrays, Empirical Bayes and the Two-Groups Model
Carl N. Morris
Statist. Sci. 23(1): 34-40 (February 2008). DOI: 10.1214/08-STS236D

Abstract

Brad Efron’s paper has inspired a return to the ideas behind Bayes, frequency and empirical Bayes. The latter preferably would not be limited to exchangeable models for the data and hyperparameters. Parallels are revealed between microarray analyses and profiling of hospitals, with advances suggesting more decision modeling for gene identification also. Then good multilevel and empirical Bayes models for random effects should be sought when regression toward the mean is anticipated.

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Carl N. Morris. "Comment: Microarrays, Empirical Bayes and the Two-Groups Model." Statist. Sci. 23 (1) 34 - 40, February 2008. https://doi.org/10.1214/08-STS236D

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Published: February 2008
First available in Project Euclid: 7 July 2008

zbMATH: 1327.62049
MathSciNet: MR2523936
Digital Object Identifier: 10.1214/08-STS236D

Rights: Copyright © 2008 Institute of Mathematical Statistics

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Vol.23 • No. 1 • February 2008
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