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May 1998 Decision analysis and bioequivalence trials
Dennis V. Lindley
Statist. Sci. 13(2): 136-141 (May 1998). DOI: 10.1214/ss/1028905932

Abstract

It is argued that the determination of bioequivalence involves a decision, and is not purely a problem of inference. A coherent method of decision-making is examined in detail for a simple trial of bioequivalence. The result is shown to differ seriously from the inferential method, using significance tests, ordinarily used. The reason for the difference is explored. It is shown how the decision-analytic method can be used in more complicated and realistic trials and the case for its general use presented.

Citation

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Dennis V. Lindley. "Decision analysis and bioequivalence trials." Statist. Sci. 13 (2) 136 - 141, May 1998. https://doi.org/10.1214/ss/1028905932

Information

Published: May 1998
First available in Project Euclid: 9 August 2002

zbMATH: 0960.62125
Digital Object Identifier: 10.1214/ss/1028905932

Keywords: Bioequivalence , Coherence , conjugacy , expected loss , Loss , sample size , Utility

Rights: Copyright © 1998 Institute of Mathematical Statistics

Vol.13 • No. 2 • May 1998
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