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2013 Hemodynamic Features in Stenosed Coronary Arteries: CFD Analysis Based on Histological Images
Mahsa Dabagh, Wakako Takabe, Payman Jalali, Stephen White, Hanjoong Jo
J. Appl. Math. 2013(SI05): 1-11 (2013). DOI: 10.1155/2013/715407


Histological images from the longitudinal section of four diseased coronary arteries were used, for the first time, to study the pulsatile blood flow distribution within the lumen of the arteries by means of computational fluid dynamics (CFD). Results indicate a strong dependence of the hemodynamics on the morphology of atherosclerotic lesion. Distinctive flow patterns appear in different stenosed regions corresponding to the specific geometry of any artery. Results show that the stenosis affects the wall shear stress (WSS) locally along the diseased arterial wall as well as other adjacent walls. The maximum magnitude of WSS is observed in the throat of stenosis. Moreover, high oscillatory shear index (OSI) is observed along the stenosed wall and the high curvature regions. The present study is capable of providing information on the shear environment in the longitudinal section of the diseased coronary arteries, based on the models created from histological images. The computational method may be used as an effective way to predict plaque forming regions in healthy arterial walls.


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Mahsa Dabagh. Wakako Takabe. Payman Jalali. Stephen White. Hanjoong Jo. "Hemodynamic Features in Stenosed Coronary Arteries: CFD Analysis Based on Histological Images." J. Appl. Math. 2013 (SI05) 1 - 11, 2013.


Published: 2013
First available in Project Euclid: 14 March 2014

zbMATH: 1271.92011
Digital Object Identifier: 10.1155/2013/715407

Rights: Copyright © 2013 Hindawi


Vol.2013 • No. SI05 • 2013
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