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2012 Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds
Chongyang Liu, Zhaohua Gong, Zhaoyi Huo, Bangyu Shen
J. Appl. Math. 2012: 1-13 (2012). DOI: 10.1155/2012/245315

Abstract

A nonlinear dynamical system, in which the feed rates of glycerol and alkali are taken as the control functions, is first proposed to formulate the fed-batch culture of 1,3-propanediol (1,3-PD) production. To maximize the 1,3-PD concentration at the terminal time, a constrained optimal control model is then presented. A solution approach is developed to seek the optimal feed rates based on control vector parametrization method and improved differential evolution algorithm. The proposed methodology yielded an increase by 32.17% of 1,3-PD concentration at the terminal time.

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Chongyang Liu. Zhaohua Gong. Zhaoyi Huo. Bangyu Shen. "Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds." J. Appl. Math. 2012 1 - 13, 2012. https://doi.org/10.1155/2012/245315

Information

Published: 2012
First available in Project Euclid: 14 December 2012

zbMATH: 1242.49087
MathSciNet: MR2898070
Digital Object Identifier: 10.1155/2012/245315

Rights: Copyright © 2012 Hindawi

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