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2024 Adaptive procedures for directional false discovery rate control
Dennis Leung, Ninh Tran
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Electron. J. Statist. 18(1): 706-741 (2024). DOI: 10.1214/24-EJS2213


In multiple hypothesis testing, it is well known that adaptive procedures can enhance power via incorporating information about the number of true nulls present. Under independence, we establish that two adaptive false discovery rate (FDR) methods, upon augmenting sign declarations, also offer directional false discovery rate (FDRdir) control in the strong sense. Such FDRdir controlling properties are appealing, because adaptive procedures have the greatest potential to reap substantial gain in power when the underlying parameter configurations contain little to no true nulls, which are precisely settings where the FDRdir is an arguably more meaningful error rate to be controlled than the FDR.


The authors would like to thank the anonymous referees and an Associate Editor for their constructive comments that improved the quality of this paper.


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Dennis Leung. Ninh Tran. "Adaptive procedures for directional false discovery rate control." Electron. J. Statist. 18 (1) 706 - 741, 2024.


Received: 1 April 2023; Published: 2024
First available in Project Euclid: 23 February 2024

Digital Object Identifier: 10.1214/24-EJS2213

Primary: 62F03
Secondary: 62C12

Keywords: Adaptive procedures , directional inference , False discovery rate , multiple testing

Vol.18 • No. 1 • 2024
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