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June 2009 ABC likelihood-free methods for model choice in Gibbs random fields
Aude Grelaud, Jean-Michel Marin, Christian P. Robert, François Rodolphe, Jean-François Taly
Bayesian Anal. 4(2): 317-335 (June 2009). DOI: 10.1214/09-BA412

Abstract

Gibbs random fields (GRF) are polymorphous statistical models that can be used to analyse different types of dependence, in particular for spatially correlated data. However, when those models are faced with the challenge of selecting a dependence structure from many, the use of standard model choice methods is hampered by the unavailability of the normalising constant in the Gibbs likelihood. In particular, from a Bayesian perspective, the computation of the posterior probabilities of the models under competition requires special likelihood-free simulation techniques like the Approximate Bayesian Computation (ABC) algorithm that is intensively used in population genetics. We show in this paper how to implement an ABC algorithm geared towards model choice in the general setting of Gibbs random fields, demonstrating in particular that there exists a sufficient statistic across models. The accuracy of the approximation to the posterior probabilities can be further improved by importance sampling on the distribution of the models. The practical aspects of the method are detailed through two applications, the test of an iid Bernoulli model versus a first-order Markov chain, and the choice of a folding structure for two proteins.

Citation

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Aude Grelaud. Jean-Michel Marin. Christian P. Robert. François Rodolphe. Jean-François Taly. "ABC likelihood-free methods for model choice in Gibbs random fields." Bayesian Anal. 4 (2) 317 - 335, June 2009. https://doi.org/10.1214/09-BA412

Information

Published: June 2009
First available in Project Euclid: 22 June 2012

zbMATH: 1330.62126
MathSciNet: MR2507366
Digital Object Identifier: 10.1214/09-BA412

Keywords: Approximate Bayesian Computation , Bayes factor , Gibbs random fields , model choice , protein folding

Rights: Copyright © 2009 International Society for Bayesian Analysis

Vol.4 • No. 2 • June 2009
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