September 2021 A multivariate spatiotemporal change-point model of opioid overdose deaths in Ohio
Staci A. Hepler, Lance A. Waller, David M. Kline
Ann. Appl. Stat. 15(3): 1329-1342 (September 2021). DOI: 10.1214/20-AOAS1415

Abstract

Ohio is one of the states most impacted by the opioid epidemic and experienced the second highest age-adjusted fatal drug overdose rate in 2017. Initially it was believed prescription opioids were driving the opioid crisis in Ohio. However, as the epidemic evolved, opioid overdose deaths due to fentanyl have drastically increased. In this work we develop a Bayesian multivariate spatiotemporal model for Ohio county overdose death rates from 2007 to 2018 due to different types of opioids. The log-odds are assumed to follow a spatially varying change point regression model. By assuming the regression coefficients are a multivariate conditional autoregressive process, we capture spatial dependence within each drug type and also dependence across drug types. The proposed model allows us to not only study spatiotemporal trends in overdose death rates but also to detect county-level shifts in these trends over time for various types of opioids.

Funding Statement

Research reported in this publication was supported by the National Institute on Drug Abuse of the National Institutes of Health under Award Number R21DA045236.

Acknowledgments

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

These data were provided by the Ohio Department of Health. The Department specifically disclaims responsibility for any analyses, interpretations or conclusions.

Citation

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Staci A. Hepler. Lance A. Waller. David M. Kline. "A multivariate spatiotemporal change-point model of opioid overdose deaths in Ohio." Ann. Appl. Stat. 15 (3) 1329 - 1342, September 2021. https://doi.org/10.1214/20-AOAS1415

Information

Received: 1 May 2020; Revised: 1 October 2020; Published: September 2021
First available in Project Euclid: 23 September 2021

MathSciNet: MR4316651
zbMATH: 1478.62327
Digital Object Identifier: 10.1214/20-AOAS1415

Keywords: Bayesian , change point , Multivariate conditional autoregressive , spatial rates

Rights: Copyright © 2021 Institute of Mathematical Statistics

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Vol.15 • No. 3 • September 2021
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