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February, 1988 Selection Models and the File Drawer Problem
Satish Iyengar, Joel B. Greenhouse
Statist. Sci. 3(1): 109-117 (February, 1988). DOI: 10.1214/ss/1177013012


Meta-analysis consists of quantitative methods for combining evidence from different studies about a particular issue. A frequent criticism of meta-analysis is that it may be based on a biased sample of all studies that were done. In this paper, we use selection models, or weighted distributions, to deal with one source of bias, namely, the failure to report studies that do not yield statistically significant results. We apply selection models to two approaches that have been suggested for correcting the bias. The fail-safe sample size approach calculates the minimum number of unpublished studies showing nonsignificant results that must have been carried out in order to overturn the conclusion reached from the published studies. The maximum likelihood approach uses a weighted distribution to model the selection bias in the generation of the data and estimates various parameters of interest. We suggest the use of families of weight functions to model plausible biasing mechanisms to study the sensitivity of inferences about effect sizes. By using an example, we show that the maximum likelihood approach has several advantages over the fail-safe sample size approach.


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Satish Iyengar. Joel B. Greenhouse. "Selection Models and the File Drawer Problem." Statist. Sci. 3 (1) 109 - 117, February, 1988.


Published: February, 1988
First available in Project Euclid: 19 April 2007

Digital Object Identifier: 10.1214/ss/1177013012

Keywords: file drawer problem , maximum likelihood estimation , Meta-analysis , selection bias , weighted distributions

Rights: Copyright © 1988 Institute of Mathematical Statistics


Vol.3 • No. 1 • February, 1988
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