Beginning with a discussion of R. A. Fisher’s early written remarks that relate to dimension reduction, this article revisits principal components as a reductive method in regression, develops several model-based extensions and ends with descriptions of general approaches to model-based and model-free dimension reduction in regression. It is argued that the role for principal components and related methodology may be broader than previously seen and that the common practice of conditioning on observed values of the predictors may unnecessarily limit the choice of regression methodology.

Increasing pressures on the environment are generating an ever-increasing need to manage animal and plant populations sustainably, and to protect and rebuild endangered populations. Effective management requires reliable mathematical models, so that the effects of management action can be predicted, and the uncertainty in these predictions quantified. These models must be able to predict the response of populations to anthropogenic change, while handling the major sources of uncertainty. We describe a simple “building block” approach to formulating discrete-time models. We show how to estimate the parameters of such models from time series of data, and how to quantify uncertainty in those estimates and in numbers of individuals of different types in populations, using computer-intensive Bayesian methods. We also discuss advantages and pitfalls of the approach, and give an example using the British grey seal population.

In this paper, we describe centering and noncentering methodology as complementary techniques for use in parametrization of broad classes of hierarchical models, with a view to the construction of effective MCMC algorithms for exploring posterior distributions from these models. We give a clear qualitative understanding as to when centering and noncentering work well, and introduce theory concerning the convergence time complexity of Gibbs samplers using centered and noncentered parametrizations. We give general recipes for the construction of noncentered parametrizations, including an auxiliary variable technique called the state-space expansion technique. We also describe partially noncentered methods, and demonstrate their use in constructing robust Gibbs sampler algorithms whose convergence properties are not overly sensitive to the data.

It has recently become popular to define treatment effects for subsets of the target population characterized by variables not observable at the time a treatment decision is made. Characterizing and estimating such treatment effects is tricky; the most popular but naive approach inappropriately adjusts for variables affected by treatment and so is biased. We consider several appropriate ways to formalize the effects: principal stratification, stratification on a single potential auxiliary variable, stratification on an observed auxiliary variable and stratification on expected levels of auxiliary variables. We then outline identifying assumptions for each type of estimand. We evaluate the utility of these estimands and estimation procedures for decision making and understanding causal processes, contrasting them with the concepts of direct and indirect effects. We motivate our development with examples from nephrology and cancer screening, and use simulated data and real data on cancer screening to illustrate the estimation methods.

Chess and chance are seemingly strange bedfellows. Luck and/or randomness have no apparent role in move selection when the game is played at the highest levels. However, when competition is at the ultimate level, that of the World Chess Championship (WCC), chess and conspiracy are not strange bedfellows, there being a long and colorful history of accusations levied between participants. One such accusation, frequently repeated, was that all the games in the 1985 WCC (Karpov vs Kasparov) were fixed and prearranged move by move. That this claim was advanced by a former World Champion, Bobby Fischer, argues that it ought be investigated. That the only published, concrete basis for this claim consists of an observed run of particular moves, allows this investigation to be performed using probabilistic and statistical methods. In particular, we employ imbedded finite Markov chains to evaluate run statistic distributions. Further, we demonstrate how both chess computers and game data bases can be brought to bear on the problem.

November 27, 2004, marked the 250th anniversary of the death of Abraham De Moivre, best known in statistical circles for his famous large-sample approximation to the binomial distribution, whose generalization is now referred to as the Central Limit Theorem. De Moivre was one of the great pioneers of classical probability theory. He also made seminal contributions in analytic geometry, complex analysis and the theory of annuities. The first biography of De Moivre, on which almost all subsequent ones have since relied, was written in French by Matthew Maty. It was published in 1755 in the Journal britannique. The authors provide here, for the first time, a complete translation into English of Maty’s biography of De Moivre. New material, much of it taken from modern sources, is given in footnotes, along with numerous annotations designed to provide additional clarity to Maty’s biography for contemporary readers.

Robert Vincent Hogg was born on November 8, 1924 in Hannibal, Missouri. He earned a Ph.D. in statistics at the University of Iowa in 1950, where his advisor was Allen Craig. Following graduation, he joined the mathematics faculty at the University of Iowa. He was the founding Chair when the Department of Statistics was created at Iowa in 1965 and he served in that capacity for 19 years. At Iowa he also served as Chair of the Quality Management and Productivity Program and the Hanson Chair of Manufacturing Productivity. He became Professor Emeritus in 2001 after 51 years on the Iowa faculty. He is a Fellow of the Institute of Mathematical Statistics and the American Statistical Association plus an Elected Member of the International Statistical Institute. He was President of the American Statistical Association (1988) and chaired two of its winter conferences (1992, 1994). He received the ASA’s Founder’s Award (1991) and the Gottfried Noether Award (2001) for contributions to nonparametric statistics. His publications through 1996 are described in Communications in Statistics—Theory and Methods (1996), 2467–2481.

This interview was conducted on April 14, 2004 at the Department of Statistics, University of Florida, Gainesville, Florida, and revised in the summer of 2006.