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2018 Modeling of breast cancer through evolutionary game theory
Ke’Yona Barton, Corbin Smith, Jan Rychtář, Tsvetanka Sendova
Involve 11(4): 541-548 (2018). DOI: 10.2140/involve.2018.11.541

Abstract

We present a simple mathematical model of the development and progression of breast cancer based on evolutionary game theory. Four types of cellular populations are considered: stromal (native) cells, macrophages, benign tumor cells, and motile (malignant) tumor cells. Despite the relative simplicity of the model, it provides a way to explore the interactions between the various cell types and suggests potential approaches to managing and treating cancer.

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Ke’Yona Barton. Corbin Smith. Jan Rychtář. Tsvetanka Sendova. "Modeling of breast cancer through evolutionary game theory." Involve 11 (4) 541 - 548, 2018. https://doi.org/10.2140/involve.2018.11.541

Information

Received: 13 January 2015; Revised: 8 July 2017; Accepted: 20 July 2017; Published: 2018
First available in Project Euclid: 28 March 2018

zbMATH: 06864395
MathSciNet: MR3778911
Digital Object Identifier: 10.2140/involve.2018.11.541

Subjects:
Primary: 91A22
Secondary: 91A40

Keywords: breast cancer , Evolutionary game theory , mathematical modeling

Rights: Copyright © 2018 Mathematical Sciences Publishers

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Vol.11 • No. 4 • 2018
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