We present a simple mathematical model of the development and progression of breast cancer based on evolutionary game theory. Four types of cellular populations are considered: stromal (native) cells, macrophages, benign tumor cells, and motile (malignant) tumor cells. Despite the relative simplicity of the model, it provides a way to explore the interactions between the various cell types and suggests potential approaches to managing and treating cancer.
"Modeling of breast cancer through evolutionary game theory." Involve 11 (4) 541 - 548, 2018. https://doi.org/10.2140/involve.2018.11.541