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June 2017 Vaccines, contagion, and social networks
Elizabeth L. Ogburn, Tyler J. VanderWeele
Ann. Appl. Stat. 11(2): 919-948 (June 2017). DOI: 10.1214/17-AOAS1023


Consider the causal effect that one individual’s treatment may have on another individual’s outcome when the outcome is contagious, with specific application to the effect of vaccination on an infectious disease outcome. The effect of one individual’s vaccination on another’s outcome can be decomposed into two different causal effects, called the “infectiousness” and “contagion” effects. We present identifying assumptions and estimation or testing procedures for infectiousness and contagion effects in two different settings: (1) using data sampled from independent groups of observations, and (2) using data collected from a single interdependent social network. The methods that we propose for social network data require fitting generalized linear models (GLMs). GLMs and other statistical models that require independence across subjects have been used widely to estimate causal effects in social network data, but because the subjects in networks are presumably not independent, the use of such models is generally invalid, resulting in inference that is expected to be anticonservative. We describe a subsampling scheme that ensures that GLM errors are uncorrelated across subjects despite the fact that outcomes are nonindependent. This simultaneously demonstrates the possibility of using GLMs and related statistical models for network data and highlights their limitations.


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Elizabeth L. Ogburn. Tyler J. VanderWeele. "Vaccines, contagion, and social networks." Ann. Appl. Stat. 11 (2) 919 - 948, June 2017.


Received: 1 November 2014; Revised: 1 February 2017; Published: June 2017
First available in Project Euclid: 20 July 2017

zbMATH: 06775898
MathSciNet: MR3693552
Digital Object Identifier: 10.1214/17-AOAS1023

Keywords: Causal inference , contagion , peer effects , social networks

Rights: Copyright © 2017 Institute of Mathematical Statistics


Vol.11 • No. 2 • June 2017
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