We consider a family of non-autonomous reaction-diffusion equations $$ u_t=\sum_{i,j=1}^N a_{ij}(\omega t)\partial_i\partial_j u+f(\omega t,u)+ g(\omega t,x), \quad x\in\mathbb R^N \tag{$\text{\rm E}_\omega$} $$ with almost periodic, rapidly oscillating principal part and nonlinear interactions. As $\omega\to \infty$, we prove that the solutions of $(\text{\rm E}_\omega)$ converge to the solutions of the averaged equation $$ u_t=\sum_{i,j=1}^N \overline a_{ij}\partial_i\partial_j u+\overline f(u)+ \overline g(x), \quad x\in\mathbb R^N. \tag{$\text{\rm E}_\infty$} $$ If $f$ is dissipative, we prove existence and upper-semicontinuity of attractors for the family (E$_\omega$) as $\omega\to\infty$.
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