Journal of Physical Mathematics

Parametric Resonance Applications in Neutrophil Dynamics

Suqi Ma and Jinzhi Lei

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The profound effects of chemotherapy on the combined dynamics of the hematological stem cells and their differentiated neutrophils is examined. G-CSF is often used to deal with this neutropenia and the response is highly variable. To shape the neutrophil response to chemotherapy and G-CSF, periodic parametric resonance is discussed. Periodic oscillation in neutrophil levels and the subharmonic 1:2 resonance phenomena are observed with the assumption of periodic chemotherapy is given. The work is aim to stimulate further investigations and the practical applications.

Article information

J. Phys. Math., Volume 7, Number 1 (2016), 3 pages.

First available in Project Euclid: 31 August 2017

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parametric resonance neutrophils hematological stem cells


Ma, Suqi; Lei, Jinzhi. Parametric Resonance Applications in Neutrophil Dynamics. J. Phys. Math. 7 (2016), no. 1, 3 pages. doi:10.4172/2090-0902.1000154.

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