Bernoulli

  • Bernoulli
  • Volume 10, Number 3 (2004), 447-463.

Asymptotic normality of urn models for clinical trials with delayed response

Feifang Hu and Li-Xin Zhang

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Abstract

For response-adaptive clinical trials using a generalized Friedman's urn design, we derive the asymptotic normality of the sample fraction assigned to each treatment under staggered entry and delayed response. The rate of convergence and the law of the iterated logarithm are obtained for both the urn composition and the sample fraction. Some applications are also discussed.

Article information

Source
Bernoulli, Volume 10, Number 3 (2004), 447-463.

Dates
First available in Project Euclid: 7 July 2004

Permanent link to this document
https://projecteuclid.org/euclid.bj/1089206406

Digital Object Identifier
doi:10.3150/bj/1089206406

Mathematical Reviews number (MathSciNet)
MR2061440

Zentralblatt MATH identifier
1054.62083

Keywords
Gaussian process generalized Friedman's urn staggered entry treatment allocation urn models

Citation

Hu, Feifang; Zhang, Li-Xin. Asymptotic normality of urn models for clinical trials with delayed response. Bernoulli 10 (2004), no. 3, 447--463. doi:10.3150/bj/1089206406. https://projecteuclid.org/euclid.bj/1089206406


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References

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