- Bayesian Anal.
- Volume 12, Number 1 (2017), 89-112.
Bayesian Nonparametric Tests via Sliced Inverse Modeling
We study the problem of independence and conditional independence tests between categorical covariates and a continuous response variable, which has an immediate application in genetics. Instead of estimating the conditional distribution of the response given values of covariates, we model the conditional distribution of covariates given the discretized response (aka “slices”). By assigning a prior probability to each possible discretization scheme, we can compute efficiently a Bayes factor (BF)-statistic for the independence (or conditional independence) test using a dynamic programming algorithm. Asymptotic and finite-sample properties such as power and null distribution of the BF statistic are studied, and a stepwise variable selection method based on the BF statistic is further developed. We compare the BF statistic with some existing classical methods and demonstrate its statistical power through extensive simulation studies. We apply the proposed method to a mouse genetics data set aiming to detect quantitative trait loci (QTLs) and obtain promising results.
Bayesian Anal. Volume 12, Number 1 (2017), 89-112.
First available in Project Euclid: 19 January 2016
Permanent link to this document
Digital Object Identifier
Mathematical Reviews number (MathSciNet)
Jiang, Bo; Ye, Chao; Liu, Jun S. Bayesian Nonparametric Tests via Sliced Inverse Modeling. Bayesian Anal. 12 (2017), no. 1, 89--112. doi:10.1214/16-BA993. https://projecteuclid.org/euclid.ba/1453211961
- Supplement to “Bayesian Nonparametric Tests via Sliced Inverse Modeling”. We provide additional supporting materials that include detailed proofs and additional empirical results.