The Annals of Statistics
- Ann. Statist.
- Volume 28, Number 5 (2000), 1452-1471.
Optimal sequential designs of case-control studies
Fixed case-control studies separately collect a case sample and a control sample withthe two sample sizes being fixed prior to studies and sometimes arbitrarily chosen. This often results in loss of efficiency of case-control designs in terms of cost-saving or time-saving of the studies. We study sequential case-control designs and, in connection with treatment allocation and stochastic approximation, derive a simple sampling rule that leads to optimal case-control designs. Some important issues suchas fixed- width confidence intervals and sequential tests of hypotheses with possible early stopping to save time or costs, whichcannot be answered with fixed case-control designs, are shown to be naturally solved with the derived optimal sequential case-control designs.
Ann. Statist., Volume 28, Number 5 (2000), 1452-1471.
First available in Project Euclid: 12 March 2002
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Chen, Kani. Optimal sequential designs of case-control studies. Ann. Statist. 28 (2000), no. 5, 1452--1471. doi:10.1214/aos/1015957402. https://projecteuclid.org/euclid.aos/1015957402