The Annals of Applied Statistics
- Ann. Appl. Stat.
- Volume 5, Number 3 (2011), 1816-1838.
Estimating within-household contact networks from egocentric data
Acute respiratory diseases are transmitted over networks of social contacts. Large-scale simulation models are used to predict epidemic dynamics and evaluate the impact of various interventions, but the contact behavior in these models is based on simplistic and strong assumptions which are not informed by survey data. These assumptions are also used for estimating transmission measures such as the basic reproductive number and secondary attack rates. Development of methodology to infer contact networks from survey data could improve these models and estimation methods. We contribute to this area by developing a model of within-household social contacts and using it to analyze the Belgian POLYMOD data set, which contains detailed diaries of social contacts in a 24-hour period. We model dependency in contact behavior through a latent variable indicating which household members are at home. We estimate age-specific probabilities of being at home and age-specific probabilities of contact conditional on two members being at home. Our results differ from the standard random mixing assumption. In addition, we find that the probability that all members contact each other on a given day is fairly low: 0.49 for households with two 0–5 year olds and two 19–35 year olds, and 0.36 for households with two 12–18 year olds and two 36+ year olds. We find higher contact rates in households with 2–3 members, helping explain the higher influenza secondary attack rates found in households of this size.
Ann. Appl. Stat., Volume 5, Number 3 (2011), 1816-1838.
First available in Project Euclid: 13 October 2011
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Potter, Gail E.; Handcock, Mark S.; Longini, Jr., Ira M.; Halloran, M. Elizabeth. Estimating within-household contact networks from egocentric data. Ann. Appl. Stat. 5 (2011), no. 3, 1816--1838. doi:10.1214/11-AOAS474. https://projecteuclid.org/euclid.aoas/1318514286
- Supplementary material A: Contact network parameters estimated separately for the holiday period versus the nonholiday period, and for 2–3 member households versus 4+ member households. We present parameter estimates computed separately for respondents who reported during the Easter holiday period and during a nonholiday period. Next we report parameters estimated separately for households with 2–3 members and those with 4+ members.
- Supplementary material B: Results from simulation study exploring weak identifiability. We present simulation results evaluating weak identifiability of our parameters in data sets with low within-household contact rates and low at-home probabilities.
- Supplementary material C: R code used for estimation, bootstrapping, and simulation in “Estimating within-household contact networks from egocentric data”. This supplement includes R code used to perform estimation, bootstrap confidence intervals, and perform a simulation study assessing weak identifiability in households with low contact rates and low probabilities of being at home.