The Annals of Statistics
- Ann. Statist.
- Volume 31, Number 4 (2003), 1110-1139.
Large sample theory for semiparametric regression models with two-phase, outcome dependent sampling
Outcome-dependent, two-phase sampling designs can dramatically reduce the costs of observational studies by judicious selection of the most informative subjects for purposes of detailed covariate measurement. Here we derive asymptotic information bounds and the form of the efficient score and influence functions for the semiparametric regression models studied by Lawless, Kalbfleisch and Wild (1999) under two-phase sampling designs. We show that the maximum likelihood estimators for both the parametric and nonparametric parts of the model are asymptotically normal and efficient. The efficient influence function for the parametric part agrees with the more general information bound calculations of Robins, Hsieh and Newey (1995). By verifying the conditions of Murphy and van der Vaart (2000) for a least favorable parametric submodel, we provide asymptotic justification for statistical inference based on profile likelihood.
Ann. Statist. Volume 31, Number 4 (2003), 1110-1139.
First available in Project Euclid: 31 July 2003
Permanent link to this document
Digital Object Identifier
Mathematical Reviews number (MathSciNet)
Zentralblatt MATH identifier
Primary: 60F05: Central limit and other weak theorems 60F17: Functional limit theorems; invariance principles
Secondary: 60J65: Brownian motion [See also 58J65] 60J70: Applications of Brownian motions and diffusion theory (population genetics, absorption problems, etc.) [See also 92Dxx]
asymptotic distributions asymptotic efficiency consistency covariates empirical processes information bounds least favorable maximum likelihood missing data profile likelihood outcome dependent stratified sampling two-phase $Z$-theorem
Breslow, Norman; McNeney, Brad; Wellner, Jon A. Large sample theory for semiparametric regression models with two-phase, outcome dependent sampling. Ann. Statist. 31 (2003), no. 4, 1110--1139. doi:10.1214/aos/1059655907. http://projecteuclid.org/euclid.aos/1059655907.