Interpreting DNA Evidence: A Review

Interpreting DNA Evidence: A Review

L.A. Foreman, C. Champod, I.W. Evett, J.A. Lambert, and S. Pope

Source: Internat. Statist. Rev. Volume 71, Number 3 (2003), 473-495.

Abstract

The paper provides a review of current issues relating to the use of DNA profiling in forensic science. A short historical section gives the main statistical milestones that occurred during a rapid development of DNA technology and operational uses. Greater detail is then provided for interpretation issues involving STR DNA profiles, including:

methods that take account of population substructure in DNA calculations;

parallel work carried out by the US National Research Council;

the move away from multiple independence testing in favour of experiments that demonstrate the robustness of casework procedures;

the questionable practice of source attribution `with reasonable scientific certainty';

the effect on the interpretation of profiles obtained under increasingly sensitive techniques, the LCN technique in particular;

the use of DNA profiles as an intelligence tool;

the interpretation of DNA mixtures.

Experience of presenting DNA evidence within UK courts is also discussed. The paper then summarises a generic interpretation framework based on the concept of likelihood ratio within a hierarchy of propositions. Finally the use of Bayesian networks to interpret DNA evidence is reviewed.

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Keywords: Forensic science; Interpretation of evidence; Likelihood ratio; DNA profile; DNA mixtures; Bayesian networks

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Zentralblatt MATH identifier: 02124737

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