Source: Ann. Statist. Volume 24, Number 2
(1996), 569-595.
In survival analysis with censored data, we consider three closely related survival function estimators: the Kaplan-Meier, Nelson and moment estimators. We derive the Edgeworth expansions for these three estimators with Studentization. Edgeworth expansions for the corresponding bootstrap statistics are also given. It is found that the bootstrap approximation is better than the normal approximation for the Studentized Kaplan-Meier and Nelson estimators, but not so for the Studentized moment estimator. With these results, we construct bootstrap-based confidence intervals with better coverage probabilities. We also include some simulations which show strong agreement with our theoretical findings.
References
ABRAMOVITCH, L. and SINGH, K. 1985. Edgeworth corrected pivotal statistics and the bootstrap. Ann. Statist. 13 116 132. Z.
AKRITAS, M. G. 1986. Bootstrapping the Kaplan Meier estimator J. Amer. Statist. Assoc. 81 1032 1038. Z.
Mathematical Reviews (MathSciNet):
MR867628
ALTSHULER, B. 1970. Theory for the measurement of competing risks in animal experiments. Math. Biosci. 6 1 11. Z.
BICKEL, P. J., GOTZE, F. and VAN ZWET, W. R. 1986. The Edgeworth expansion for U-statistics of ¨ degree two. Ann. Statist. 14 1463 1484. Z.
BRESLOW, N. and CROWLEY, J. 1974. A large sample study of the life table and product-limit estimates under random censorship. Ann. Statist. 2 437 453. Z.
CALLARET, H. and VERAVERBEKE, N. 1981. The order of the normal approximation for a Studentized U-statistic. Ann. Statist. 9 194 200. Z.
Mathematical Reviews (MathSciNet):
MR600547
CHEN, K. and YING, Z. 1996. A counterexample to a conjecture on Hall Wellner band. Ann. Statist. 24 641 646. Z.
CUZICK, J. 1985. Asy mptotic properties of censored linear rank tests. Ann. Statist. 13 133 141. Z.
EFRON, B. 1981. Censored data and the bootstrap. J. Amer. Statist. Assoc. 76 312 319. Z.
GILL, R. D. 1983. Large sample behavior of the product-limit estimator on the whole line. Ann. Statist. 11 49 58. Z.
Mathematical Reviews (MathSciNet):
MR684862
GREENWOOD, M. 1926. The natural duration of cancer. In Report on Public Health and Medical Subjects 33 1 26. Her Majesty's Stationary Office, London. Z. Z.
HALL, P. 1988. Theoretical comparison of bootstrap confidence intervals with discussion. Ann. Statist. 16 927 981.
Mathematical Reviews (MathSciNet):
MR959185
HALL, P. 1992. The Bootstrap and Edgeworth Expansion. Springer, Berlin. Z.
HALL, W. J. and WELLNER, J. A. 1980. Confidence bands for a survival curve from censored data. Biometrika 67 133 143. Z.
Mathematical Reviews (MathSciNet):
MR570515
HELMERS, R. 1991. On the Edgeworth expansion and the bootstrap approximation for a Studentized U-statistic. Ann. Statist. 19 470 484. Z.
KAPLAN, E. L. and MEIER, P. 1958. Nonparametric estimation from incomplete observations. J. Amer. Statist. Assoc. 53 457 481. Z.
Mathematical Reviews (MathSciNet):
MR93867
LO, S-H. and SINGH, K. 1986. The product-limit estimator and the bootstrap: some asy mptotic representations. Probab. Theory Related Fields 71 455 465. Z.
PRENTICE, R. L. 1978. Linear rank tests with right censored data. Biometrika 65 167 179.
KOWLOON, HONG KONG COLUMBIA UNIVERSITY