Source: Adv. in Appl. Probab. Volume 41, Number 4
(2009), 1059-1081.
We consider a branching model for a population of dividing cells infected by parasites. Each cell receives parasites by
inheritance from its mother cell and independent contamination from outside the cell population. Parasites multiply
randomly inside the cell and are shared randomly between the two daughter cells when the cell divides. The law
governing the number of parasites which contaminate a given cell depends only on whether the cell is already infected
or not. We first determine the asymptotic behavior of branching processes in a random environment with state-dependent
immigration, which gives the convergence in distribution of the number of parasites in a cell line. We then derive a
law of large numbers for the asymptotic proportions of cells with a given number of parasites. The main tools are
branching processes in a random environment and laws of large numbers for a Markov tree.
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References
Asmussen, S. and Hering, H. (1983). Branching Processes (Progress Prob. Statist. 3), Birkhäuser, Boston, MA.
Mathematical Reviews (MathSciNet):
MR701538
Athreya, K. B. and Karlin, S. (1971). Branching processes with random environments. II. Limit theorems. Ann. Math. Statist. 42, 1843--1858.
Mathematical Reviews (MathSciNet):
MR298781
Athreya, K. B. and Karlin, S. (1971). On branching processes with random environments. I. Extinction probabilities. Ann. Math. Statist. 42, 1499--1520.
Mathematical Reviews (MathSciNet):
MR298780
Athreya, K. B. and Ney, P. E. (2004). Branching Processes. Dover Publications, Mineola, NY.
Athreya, K. B. and Kang, H.-J. (1998). Some limit theorems for positive recurrent branching Markov chains. I. Adv. Appl. Prob. 30, 693--710.
Athreya, K. and Kang, H.-J. (1998). Some limit theorems for positive recurrent branching Markov chains. II. Adv. Appl. Prob. 30, 711--722.
Afanasyev, V. I., Geiger, J., Kersting, G. and Vatutin, V. A. (2005). Criticality for branching processes in a random environment. Ann. Prob. 33, 645--673.
Bansaye, V. (2008). Proliferating parasites in dividing cells: Kimmel's branching model revisited. Ann. Appl. Prob. 18, 967--996.
Benjamini, I. and Peres, Y. (1994). Markov chains indexed by trees. Ann. Prob. 22, 219--243.
Feller, W. (1966). An Introduction to Probability Theory and Its Applications, Vol. II. John Wiley, New York.
Mathematical Reviews (MathSciNet):
MR210154
Geiger, J., Kersting, G. and Vatutin, V. A. (2003). Limit theorems for subcritical branching processes in a random environment. Ann. Inst. H. Poincaré Prob. Statist. 39, 593--620.
Guyon, J. (2007). Limit theorems for bifurcating Markov chains. Application to the detection of cellular aging. Ann. Appl. Prob. 17, 1538--1569.
Key, E. S. (1987). Limiting distributions and regeneration times for multitype branching processes with immigration in a random environment. Ann. Prob. 15, 344--353.
Mathematical Reviews (MathSciNet):
MR877607
Kendall, D. G. (1959). Unitary dilations of Markov transition operators, and the corresponding integral representations for transition-probability matrices. In Probability and Statistics: The Harald Cramér Volume, John Wiley, New York, pp. 139--161.
Mathematical Reviews (MathSciNet):
MR116389
Kimmel, M. (1997). Quasistationarity in a branching model of division-within-division. In Classical and Modern Branching Processes (Minneapolis, MN, 1994; IMA Vol. Math. Appl. 84), Springer, New York, pp. 157--164.
Kozlov, M. V. (1976). The asymptotic behavior of the probability of non-extinction of critical branching processes in a random environment. Theory Prob. Appl. 21, 813--825.
Mathematical Reviews (MathSciNet):
MR428492
Lyons, R. and Peres, Y. (2005). Probability on Trees and Networks. Available at http://mypage.iu.edu/$\sim$rdlyons/prbtree/prbtree.html.
Roitershtein, A. (2007). A note on multitype branching processes with immigration in a random environment. Ann. Prob. 35, 1573--1592.
Smith, W. L. and Wilkinson, W. E. (1969). On branching processes in random environments. Ann. Math. Statist. 40, 814--827.
Mathematical Reviews (MathSciNet):
MR246380
Stewart, E. J., Madden, R., Paul, G. and Taddei, F. (2005). Aging and death in an organism that reproduces by morphologically symmetric division. PLoS Biol. 3, e45.